Effect of dietary sodium reduction on red blood cell sodium concentration and sodium-lithium countertransport.

Red blood cell lithium-sodium countertransport in the tecumseh blood pressure study.

Human essential hypertension has more than one cause, but to dissect out subtypes, markers are required. The maximal activity of red blood cell lithium-sodium countertransport has been shown to be increased in hypertensive patients in case-control and population-based studies; in the latter, its distribution is a mixture of two overlapping but distinguishable subpopulations. In the present stud...

Difference between human red blood cell Na+-Li+ countertransport and renal Na+-H+ exchange.

Several laboratories have reported that the activities of sodium-lithium countertransport are increased in red blood cells from patients with essential hypertension. Based on the many similarities between this transport system and the renal sodium-proton exchanger, a hypothesis has been put forth in the literature that increased red blood cell sodium-lithium countertransport activity may be a m...

Clinical Studies Difference Between Human Red Blood Cell Na-Li Counter transport and Renal Na-H Exchange

Several laboratories have reported that the activities of sodium-lithium countertransport are increased in red blood cells from patients with essential hypertension. Based on the many similarities between this transport system and the renal sodium-proton exchanger, a hypothesis has been put forth in the literature that increased red blood cell sodium-lithium counter-transport activity may be a ...

Epidemiological studies of sodium transport and hypertension.

Red blood cell membrane cation transport was measured in five population-based surveys and two randomized, controlled, dietary intervention studies to examine its associations with demographic, biological, and dietary variables in free-living individuals. A total of 508 individuals, 255 with high blood pressure, were studied. Both sexes, blacks and whites, and several age groups were represente...

Uremia and red blood cell lithium-sodium countertransport.